Realistic modelling of irregular slabs under extreme loading

This paper presents a new triangular flat shell element for reinforced concrete slabs of complex planar configuration subjected to extreme loading. The element is developed within a co-rotational framework, and it incorporates the effects of geometric as well as material non-linearities. To improve the approximation of the solution, additional hierarchic parameters are introduced within the local system of the element. The element formulation allows for composite action between different layers under the assumption of perfect bond between the slab concrete material, the reinforcement layers and the steel deck for composite slabs. To account for floor slabs of irregular geometric configurations, due allowance is made for uniaxial reinforcement to be oriented arbitrarily within the slab plane. The paper briefly describes the element formulation followed by several numerical verification examples. The applicability of the element to modelling concrete slabs is demonstrated using several validation studies against existing experimental results. The versatility of the element is further exemplified with a realistic large-scale floor slab model subjected to extreme loading scenarios. It is shown that the developed element provides a good balance between accuracy and efficiency in the modelling of irregular floor slabs subject to extreme loading conditions

Adsorption in non interconnected pores open at one or at both ends: A reconsideration of the origin of the hysteresis phenomenon

We report on an experimental study of adsorption isotherme of nitrogen onto porous silicon with non interconnected pores open at one or at both ends in order to check for the first time the old (1938) but always current idea based on Cohan's description which suggests that the adsorption of gaz should occur reversibly in the first case and irreversibly in the second one. Hysteresis loops, the shape of which is usually associated to interconnections in porous media, are observed whether the pores are open at one or at both ends in contradiction with Cohan's model.Comment: 5 pages, 4 EPS figure

Adsorption-Induced Deformation in Nanopores: Unexpected Results Obtained by Molecular Simulations

International audienceThe adsorption of a fluid in a nanoporous material induces deformations of the solid. The saturating regime, where the solid is filled with liquid, generally exhibits a linear relationship between the liquid pressure and the solid strain. This provides an experimental way to measure the elastic moduli of the solid walls. For large pores, the strain is determined by the pressure of the liquid saturating the pores and the mechanical properties of the porous solid. What happens at the nanometric scale, where liquid/matrix interfacial effects dominate? We have performed molecular simulations of a simple Lennard-Jones fluid confined between deformable nanoplatelets. The simulations provide the deformation of the nanopore as a function of the liquid pressure, in a way similar to what is done experimentally. The results show unexpected interface effects, which could be relevant to experimental data analysis

Possible Effects of Noncommutative Geometry on Weak CP Violation and Unitarity Triangles

Possible effects of noncommutative geometry on weak CP violation and unitarity triangles are discussed by taking account of a simple version of the momentum-dependent quark mixing matrix in the noncommutative standard model. In particular, we calculate nine rephasing invariants of CP violation and illustrate the noncommutative CP-violating effect in a couple of charged D-meson decays. We also show how inner angles of the deformed unitarity triangles are related to CP-violating asymmetries in some typical B_d and B_s transitions into CP eigenstates. B-meson factories are expected to help probe or constrain noncommutative geometry at low energies in the near future.Comment: RexTev 16 pages. Modifications made. References added. Accepted for publication in Phys. Rev.

A Hydrophobic Gate in an Ion Channel: The Closed State of the Nicotinic Acetylcholine Receptor

The nicotinic acetylcholine receptor (nAChR) is the prototypic member of the `Cys-loop' superfamily of ligand-gated ion channels which mediate synaptic neurotransmission, and whose other members include receptors for glycine, gamma-aminobutyric acid, and serotonin. Cryo-electron microscopy has yielded a three dimensional structure of the nAChR in its closed state. However, the exact nature and location of the channel gate remains uncertain. Although the transmembrane pore is constricted close to its center, it is not completely occluded. Rather, the pore has a central hydrophobic zone of radius about 3 A. Model calculations suggest that such a constriction may form a hydrophobic gate, preventing movement of ions through a channel. We present a detailed and quantitative simulation study of the hydrophobic gating model of the nicotinic receptor, in order to fully evaluate this hypothesis. We demonstrate that the hydrophobic constriction of the nAChR pore indeed forms a closed gate. Potential of mean force (PMF) calculations reveal that the constriction presents a barrier of height ca. 10 kT to the permeation of sodium ions, placing an upper bound on the closed channel conductance of 0.3 pS. Thus, a 3 A radius hydrophobic pore can form a functional barrier to the permeation of a 1 A radius Na+ ion. Using a united atom force field for the protein instead of an all atom one retains the qualitative features but results in differing conductances, showing that the PMF is sensitive to the detailed molecular interactions.Comment: Accepted by Physical Biology; includes a supplement and a supplementary mpeg movie can be found at http://sbcb.bioch.ox.ac.uk/oliver/download/Movies/watergate.mp

GPML: an XML-based standard for the interchange of genetic programming trees

We propose a Genetic Programming Markup Language (GPML), an XML based standard for the interchange of genetic programming trees, and outline the benefits such a format would bring in allowing the deployment of trained genetic programming (GP) models in applications as well as the subsidiary benefit of allowing GP researchers to directly share trained trees. We present a formal definition of this standard and describe details of an implementation. In addition, we present a case study where GPML is used to implement a model predictive controller for the control of a building heating plant

Increasing contextual information by merging existing archaeological data with the state of the art laser scanning in the prehistoric funerary deposit of Pastora Cave, Eastern Spain

In this paper we present a virtual reconstruction of prehistoric funerary practices in Pastora Cave,a collective burial site in Eastern Spain that dates from the Late Neolithic, Chalcolithic and Bronze Age. Modern data of the cave was captured by 3D laser scanning techniques and added to recorded archaeological data and 3D graphic information. The combination of these data sets allowed us to create a hypothetical reconstruction to analyze the material excavated in the 1940s and 50s in greater spatial context. A 3D model of the current cave was created in order to serve as a basis for modeling the relative stratigraphic information available. We present the methodology employed and the results and implications of the analysis for Pastora Cave with particular emphasis on the spatial and chronological data

Conocer para valorar y respetar : El arroyo del Azul desde la perspectiva ambiental

En las actividades desarrolladas se introducen conceptos, mensajes enfáticos sobre la importancia de las prácticas conservacionistas y los problemas relacionados con la alteración del hábitat, cambio de uso del suelo, contaminación por agroquímicos, paisaje previo a la conquista, acerca de los pueblos originarios, el proceso de agriculturación y otros temas que en base al interés de docentes y alumnos se abordaban con mayor o menor grado de profundidad. Todo ello con la intención de conocer el contexto regional y una manera sencilla de entender diversos procesos ecológicos que ocurren en la cuenca del arroyo del Azul. Las actividades de aulataller, se basan en que el conocimiento de diferentes aspectos vinculados al Arroyo del Azul, puede generar mayor conciencia por el cuidado del medio ambiente en la comunidad educativa, futuros habitantes; la identificación y reconocimiento de diferentes componentes relevantes de la fauna, flora, aspectos históricos, culturales, hidrográficos, podría actuar como disparador de otras acciones propias de la educación ambiental. El objetivo es brindar diferentes aspectos ambientales del Arroyo del Azul, como el inicio o incentivo de la responsabilidad en lo ambiental y la alfabetización ecológica. Los alumnos universitarios participantes, futuros docentes, adquieren experiencia en el mismo escenario de trabajo.Facultad de Humanidades y Ciencias de la Educació

Twenty Thousand-Year-Old Huts at a Hunter-Gatherer Settlement in Eastern Jordan

Ten thousand years before Neolithic farmers settled in permanent villages, hunter-gatherer groups of the Epipalaeolithic period (c. 22–11,600 cal BP) inhabited much of southwest Asia. The latest Epipalaeolithic phase (Natufian) is well-known for the appearance of stone-built houses, complex site organization, a sedentary lifestyle and social complexity—precursors for a Neolithic way of life. In contrast, pre-Natufian sites are much less well known and generally considered as campsites for small groups of seasonally-mobile hunter-gatherers. Work at the Early and Middle Epipalaeolithic aggregation site of Kharaneh IV in eastern Jordan highlights that some of these earlier sites were large aggregation base camps not unlike those of the Natufian and contributes to ongoing debates on their duration of occupation. Here we discuss the excavation of two 20,000-year-old hut structures at Kharaneh IV that pre-date the renowned stone houses of the Natufian. Exceptionally dense and extensive occupational deposits exhibit repeated habitation over prolonged periods, and contain structural remains associated with exotic and potentially symbolic caches of objects (shell, red ochre, and burnt horn cores) that indicate substantial settlement of the site pre-dating the Natufian and outside of the Natufian homeland as currently understood

Social visual attentional engagement and memory in Phelan-McDermid syndrome and autism spectrum disorder: a pilot eye tracking study

Background The current study used eye tracking to investigate attention and recognition memory in Phelan-McDermid syndrome (PMS), a rare genetic disorder characterized by intellectual disability, motor delays, and a high likelihood of comorbid autism spectrum disorder (ASD). Social deficits represent a core feature of ASD, including decreased propensity to orient to or show preference for social stimuli. Methods We used a visual paired-comparison task with both social and non-social images, assessing looking behavior to a novel image versus a previously viewed familiar image to characterize social attention and recognition memory in PMS (n = 22), idiopathic ASD (iASD, n = 38), and typically developing (TD) controls (n = 26). The idiopathic ASD cohort was divided into subgroups with intellectual disabilities (ID; developmental quotient 70) and the PMS group into those with and without a co-morbid ASD diagnosis. Results On measures of attention, the PMS group with a comorbid ASD diagnosis spent less time viewing the social images compared to non-social images; the rate of looking back and forth between images was lowest in the iASD with ID group. Furthermore, while all groups demonstrated intact recognition memory when novel non-social stimuli were initially presented (pre-switch), participants with PMS showed no preference during the post-switch memory presentation. In iASD, the group without ID, but not the group with ID, showed a novelty preference for social stimuli. Across indices, individuals with PMS and ASD performed more similarly to PMS without ASD and less similarly to the iASD group. Conclusion These findings demonstrate further evidence of differences in attention and memory for social stimuli in ASD and provide contrasts between iASD and PMS